Short CV (for a full CV click here)

CURRENT POSITIONS & AFFILIATIONS:

Professor of Biology (2010 - present) University of New Brunswick, Department of Biology, Fredericton, New Brunswick, Canada

Director of Education and Outreach (2011 - 2015) Center for Evolution and Cancer, University of California San Francisco, USA

External Faculty (2011 - present)  Center for Evolution and Cancer, University of California at San Francisco, USA

Adjunct Faculty (2002 - present) University of Arizona, Department of Ecology and Evolutionary Biology, Tucson, USA

RECENT PAPERS (for other papers and downloads go to Publications):

May AN, Crawford B, AM Nedelcu. 2018. In Vitro Model-Systems to Understand the Biology and Clinical Significance of Circulating Tumor Cell Clusters. Frontiers in Oncology 8:63.

Nedelcu AM. 2017. Understanding ancient legacies to expose and exploit cancer's evolutionary vulnerabilities. In Ujvari B, Roche B, Thomas F (Eds) Ecology and Evolution of Cancer. Pp 203-209. Elsevier.

Figueroa-Martinez F, Nedelcu AM, Reyes-Prieto A, and DR Smith. 2017. The plastid genomes of nonphotosynthetic algae are not so small after all. Communicative & Integrative Biology 10:1, e1283080.

Figueroa-Martinez F, Nedelcu AM, Smith DR, and A Reyes-Prieto. 2017. The plastid genome of Polytoma uvella is the largest known among non-photosynthetic algae and plants and reflects contrasting evolutionary paths to nonphotosynthetic lifestyles. Plant Physiology 173: 932-943.

Nedelcu AM and AF Caulin. 2016. The evolution of cancer suppressor mechanisms. In Maley CC (ed) Frontiers in Cancer Research: Evolutionary Foundations, Revolutionary Directions . Pp. 217-246. Springer.

Olson BJSC and AM Nedelcu. 2016 Co-option during the evolution of multicellularity and developmental complexity in the volvocine green algae. Current Opinion in Genetics & Development 39:107-115.

Koenig SG and AM Nedelcu 2016. The mechanistic basis for the evolution of soma during the transition to multicellularity in the volvocine algae. In Newman SA and Niklas K (eds) Multicellularity: Origins and Evolution. Pp. 43-70. Vienna Series in Theoretical Biology. MIT Press.

Figueroa-Martinez F, Nedelcu AM, Smith DR, A Reyes-Prieto. 2015. When the lights go out: the evolutionary fate of free-living colorless green algae. New Phytologist 206:972-982.

Kessler JO, Nedelcu AM, CA Solari, and Shelton DE. 2015. Cells acting as lenses: A possible role for light in the evolution of morphological asymmetry in multicellular volvocine algae. In Ruiz-Trillo I and AM Nedelcu (eds) Evolutionary transitions to multicellular life: Principles and Mechanisms. Pp. 225-243. Springer.

Herron MD and AM Nedelcu. 2015. Volvocine algae: from simple to complex multicellularity. In Ruiz-Trillo I and AM Nedelcu (eds) Evolutionary transitions to multicellular life: Principles and Mechanisms. Pp. 129-152. Springer.

Nedelcu AM. Volvox. (in press). In World Book Encyclopedia. World Book Publishing.

Keeling PJ et al. 2014. The Marine Microbial Eukaryote Transcriptome Sequencing Project (MMETSP): Illuminating the functional diversity of eukaryotic life in the oceans through transcriptome sequencing. PLoS Biology. 12(6): e1001889

Sprouffske K, Aktipis CA,  Radich JP, Carroll M, Nedelcu AM, and Maley CC. 2013. An evolutionary explanation for the presence of cancer non-stem cells in neoplasms. Evolutionary Applications 6:92-101.

Lang BF and AM Nedelcu. 2012. Plastid genomes of algae. In Bock R and Knoop V (eds) Genomics of Chloroplasts and Mitochondria. Advances in Photosynthesis and Respiration Series. Vol 35. pp. 59-87. Springer.

Burger G and AM Nedelcu.  2012. Mitochondrial genomes of algae. In Bock R and Knoop V (eds) Genomics of Chloroplasts and Mitochondria. Advances in Photosynthesis and Respiration Series. Vol. 35. pp. 127-157. Springer.

Nedelcu AM. 2012. Evolution of multicellularity. In: eLS (Encyclopedia of Life Sciences) 2012, John Wiley & Sons, Ltd: Chichester http://www.els.net/ [DOI:10.1002/9780470015902.a0023665].

Nedelcu AM. 2012. On the evolution of self during the transition to multicellularity.  In Carlos Lopez-Larrea (ed) Self and Non-self. pp. 14-30. Landes Biosciences.

Nedelcu AM and RE Michod.  2011. Molecular mechanisms of life history trade-offs and the evolution of multicellular complexity in volvocalean green algae. In Flatt T and Heyland A (eds) Mechanisms of Life History Evolution: The Genetics and Physiology of Life History traits and Trade-Offs. pp. 271-283. Oxford University Press.

Nedelcu AM, Driscoll WW, Durand PM, Herron M, and Rashidi E. 2011. On the paradigm of altruistic suicide in the unicellular world. Evolution 65:3-20.

Prochnik SE, Umen J, Nedelcu AM et al. 2010. Genomic analysis of organismal complexity in the multicellular green alga Volvox carteri. Science 329:223-226.

RECENT PRESENTATIONS (go to Meetings):

Evolutionary vulnerabilities in cancer: Insights from unicellular lineages. 1^st Conference on Evolution and Cancer. Center for Evolution and Cancer. UCSF, San Francisco, USA. 2011

Stress responses and life history evolution in the unicellular world. Workshop on Environmental changes and the evolution of marine ecosystems. French National Agency for Research (ANR) and TARA OCEANS – Atelier de Reflexion Prospective. Stazione Zoologica A. Dohrn, Naples, Italy. 2011.

Co-opting environmentally-induced responses for group advantage. 2010. Biocomplexity XI Workshop. The Evolution of Cooperation: Paradoxes of Collectivity & Individuality. Bloomington, IN, USA.

General acclimation responses co-opted for somatic cell differentiation in Volvox carteri. 2010. 14th International Conference on the Cell and Molecular Biology of Chlamydomonas, Norton, MA, USA.

RECENT FUNDING

NSF Collaborative Research: De Novo Evolution of Multicellularity in a Unicellular Volvocine Alga (Co-PI; with Matthew Herron and Frank Rosenzweig, U. Montana; William Ratcliff, Georgia Inst. Tech., USA) (2015-2019)

NSERC Discovery Grant: Cellular stress responses in the evolution of multicellular complexity (2013-2019)

National Center for Genome Resources (USA) and the Gordon and Betty Moore Foundation Marine Microbiology Initiative: Transcriptome sequencing of marine eukaryotic algae (Co-PI; with David R. Smith, UBC, Canada) (2011)

NSERC Discovery Grant: The genetic basis for the evolution of altruism during the transition to multicellularity (2008-2013)

NSF: Life-history trade-offs and the evolution of multicellularity (Co-PI; PI: Richard E. Michod, U Arizona, USA) (2008-2009)

NSERC Discovery grant: "An alternative framework for understanding evolutionary transitions: the green algal group as a model-system" (2003-2008)

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Last updated: January 1, 2015.